Resveratrol–a boon for treating Alzheimer’s disease?

Yazan: admin | 03 September 2008 | No Comments
Categories: Alzheimers

Resveratrol, a red wine polyphenol, is known to protect against cardiovascular diseases and cancers, as well as to promote antiaging effects in numerous organisms. It also modulates pathomechanisms of debilitating neurological disorders, such as strokes, ischemia, and Huntington’s disease. The role of resveratrol in Alzheimer’s disease is still unclear, although some recent studies on red [...]

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.

Yazan: admin | 03 September 2008 | No Comments
Categories: Diabetes

Calorie restriction extends lifespan and produces a metabolic profile desirable for treating diseases of ageing such as type 2 diabetes. SIRT1, an NAD+-dependent deacetylase, is a principal modulator of pathways downstream of calorie restriction that produce beneficial effects on glucose homeostasis and insulin sensitivity. Resveratrol, a polyphenolic SIRT1 activator, mimics the anti-ageing effects of calorie [...]

Scientists Weigh Mechanisms, Effects of Calorie Restriction

Yazan: admin | 03 September 2008 | No Comments
Categories: Uncategorized

Back in 1934, dust storms rolled across the Great Plains, Anything Goes premiered on Broadway, the New Deal was still new, and Bonnie and Clyde met their demise. During that year, too, scientists at Cornell University observed that lab rats fed a calorie-restricted diet had twice the lifespan of other rats. Those observations, reported the [...]

Can We Prevent Aging?

Yazan: admin | 03 September 2008 | No Comments
Categories: Anti Aging

People are living longer. In 1970, the average life expectancy at birth was 70.8 years; in 2000, it was 76.9 years; and by 2030 is it estimated that the “oldest-old,” age 85 and older, could grow to 10 million people. Views on aging are also changing. It no longer necessarily means physical decline and illness—in [...]

Resveratrol Found to Improve Health, But Not Longevity in Aging Mice on Standard Diet

Yazan: admin | 03 September 2008 | No Comments
Categories: Resveratrol

Scientists have found that the compound resveratrol slows age-related deterioration and functional decline of mice on a standard diet, but does not increase longevity when started at middle age. This study, conducted and supported in part by the National Institute on Aging (NIA), part of the National Institutes of Health, is a follow-up to 2006 [...]