Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation.

Yazan: admin | 03 September 2008 | 1 Comment
Categories: Resveratrol

Resveratrol, an antioxidant polyphenol from red wine, has been the subject of intense interest in recent years due to a range of unique anti-aging properties. These include cardiovascular benefits via increased nitric oxide production, down-regulation of vasoactive peptides, lowered levels of oxidized low-density lipoprotein, and cyclooxygenase inhibition; possible benefits on Alzheimer’s disease by breakdown of [...]

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.

Yazan: admin | 03 September 2008 | No Comments
Categories: Diabetes

Calorie restriction extends lifespan and produces a metabolic profile desirable for treating diseases of ageing such as type 2 diabetes. SIRT1, an NAD+-dependent deacetylase, is a principal modulator of pathways downstream of calorie restriction that produce beneficial effects on glucose homeostasis and insulin sensitivity. Resveratrol, a polyphenolic SIRT1 activator, mimics the anti-ageing effects of calorie [...]